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Optimum Nutrition Evaluation

The Optimum Nutrition Evaluation (ONE) Profile

One of the best ways to measure your health status is by looking at the end products of your metabolism, found in your urine – these “metabolic leftovers” can indicate subtle changes in your functional balance, and can identify blocks or bottlenecks in your metabolism that are affecting your health. Some of the most useful compounds in the urine for assessing your overall health are amino acids and organic acids.

Amino acids are the building blocks for every protein in your body, which includes muscles, bones, organs, nerves, membranes, hormones, neurotransmitters, and more. Organic acids are the currency of energy throughout your body and reflect your energy production capacity. Organic acids can also reveal yeast or bacterial infections or problems in your ability to detoxify toxins and chemicals. Relative levels of specific amino acids and organic acids can identify functional deficiencies of many critical vitamins, minerals, and essential nutritional co-factors.

The Optimum Nutrition Evaluation (ONE) Profile, developed by Genova Diagnostics with the assistance of Dr. Culp, measures 90 amino and organic acids and gives us a unique insight into how your body is functioning. A ONE profile identifies your unique nutritional needs and specific areas of your metabolism that need additional support for you to achieve optimal health.

The ONE Profile assesses your health for:

  • Maldigestion and Intestinal Malabsorption

  • Growth of Abnormal Bacteria & Yeast (Dysbiosis)

  • Functional Deficiencies of Vitamins, Mineral, & Nutritional Cofactors

  • Deficiencies of 20 Essential & Non-Essential Amino Acids

  • Metabolic Fatigue & Impaired Energy Production

  • Muscle Wasting & Impaired Connective Tissue Synthesis

  • Defective Detoxification Capacity

  • Neurological Imbalances – Serotonin, Dopamine, Adrenaline, Acetylcholine, GABA, Glutamate, Glycine, etc.

  • Oxidative Stress, Antioxidant Reserve, Damaged DNA and Cell Membranes

  • Inadequate Methylation (which identifies increased risks for Heart Disease, Senility, Alzheimer’s Disease, Breast, Colon, & Prostate Cancer, and Birth Defects)

Scientists have discovered that it is actually very difficult to measure FUNCTIONAL levels of vitamins, minerals and other nutrients for the simple reason that they all function INSIDE your cells. Measuring blood levels of nutrients only tells us how much is in your blood but tells us very little about your functional levels. What is critically important for your health is THE LEVEL OF NUTRIENTS INSIDE YOUR CELLS, and it is impossible to measure these levels directly. However, by measuring amino and organic acids and their metabolites and break-down products, we can create an extremely accurate picture of the nutrient levels in your cells and consequently of your cellular health for many vital nutrients.

In addition, a ONE Profile does not give just one indicator for a specific nutrient deficiency, but generally there are many indicators of problems with individual nutrients. For instance, there are 9 organic and amino acids that can indicate a problem with your folic acid metabolism. More markers out of balance indicate a more severe deficiency. In most cases, 5-10 metabolites are used to determine your functional need for any given specific nutrient.

Simply put, you are only as healthy as your cells, and your cells’ metabolism reveal your functional nutrient deficiencies.

The ONE Profile is the best diagnostic tool currently available to determine your functional need for:

  • Vitamins B1, B2, B3, B5, B6, B9 (folic acid), and B12

  • Vitamin C, Vitamin E

  • Damaged DNA and cell membranes (increased oxidative stress)

  • Specific Minerals: Magnesium, Manganese, Copper, Iron, and Zinc

  • Glutathione, alpha-Lipoic Acid, Coenzyme Q10, Carnitine

The cost for the ONE Profile is £330, paid directly to Genova Diagnostics Laboratory when you send in your urine sample for analysis. Results take approximately 3-4 weeks for completion.